Officers are becoming increasingly concerned for missing girl Alex, from Leek.
Alex, aged 16, was last seen by officers working for British Transport Police at around 7pm yesterday (21st October) at Manchester Piccadilly Station.
She is known to frequent the Leek, Manchester, Congleton and Macclesfield areas.
Alex is described as white, around 5ft 7ins tall, of a slim build with long brown hair.
She was last seen wearing a white fluffy coat and grey leggings. She also wears fake eyelashes.
Anyone who has seen Alex or anyone with information about her whereabouts is asked to call 101, quoting incident number 614 of 21st October.